Home : Unsafe Drugs : Enbrel

Enbrel Side Effects

Name: Enbrel
Generic: Etanercept
Manufacturer: Amgen and Wyeth
Date approved: 1998
Status: Prescription only - Black Box Warning
Approved uses: Rheumatoid arthritis, psoriasis, ankylosing spondylitis, psoriatic arthritis, and juvenile rheumatoid arthritis.
Off-Label uses: None
Side effects:
  • Dry cough
  • fever
  • weight loss
  • night sweats;
  • fever with chills
  • body aches
  • flu symptoms;
  • signs of skin infection such as itching
  • swelling
  • warmth
  • redness
  • or oozing; pale skin
  • easy bruising or bleeding
  • unusual weakness; black
  • bloody
  • or tarry stools; feeling short of breath
  • even with mild exertion; swelling
  • rapid weight gain; joint pain or swelling with fever
  • swollen glands
  • muscle aches
  • nausea
  • vomiting
  • chest pain
  • unusual thoughts or behavior
  • and/or seizure (convulsions); patchy
Related topics: Cimzia, Humira, Remicade
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Enbrel (Etanercept)

Enbrel (Etanercept) is an immunosuppresant, approved by the FDA for the treatment of rheumatoid arthritis, and juvenile arthritis. It is administered through a subcutaneous injection.

The most common side effects of Enbrel are dry cough, fever, weight loss, night sweats; fever with chills, body aches, flu symptoms. Patients taking Enbrel are at increased risk for serious adverse effects, including serious infections that can lead to hospitalization or death. Because Cimzia affects the immune system, it can lower the body's ability to fight infections, such as tuberculosis and other opportunistic infections. Enbrel is a blocker of TNF (tumor necrosis factor) and may cause lymphomas (a form of cancer) and other malignancies.

Recently, Enbrel was given a Black Box Label Warning by the FDA. The Black Box Warning is the strongest warning label a drug can have applied to it. Drugs that carry a high risk of serious side effects or potentially deadly adverse reactions are given this warning. This label is given only after medical studies have indicated that there are serious risks associated with the side effects of the medication.

FDA Announces Black Box Label Warning for Enbrel

In early September, 2008, the FDA announced it would require stronger warnings for four medications commonly used in the treatment of rheumatoid arthritis. These drugs suppress the immune system's reaction to illnesses, decreasing the body's ability to fight off disease and infections. A distinct fungal infection known as histoplasmosis was reported in numerous patients taking the drugs. read more

View the Enbrel Law Articles page here

Enbrel News Articles

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Enbrel Newsfeeds

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Enbrel Wikipedia

Etanercept

Tumor necrosis factor

View the Enbrel Wikipedia page here

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